PathMD Quizes, Clinical Blood Bank – 01 October 29, 2017 peferguson Author: Krishna Oza, M.D. Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. ABO system is the most important blood group system becauseIt is the first system to be described by Karl Landsteiner in 1901 Antibodies to ABO antigens are IgG typeABO antibodies are alloantibodies produced after exposure to respective antigens ABO antibodies are naturally occurring 37 degrees reactive and complement fixing antibodies 2. The glycosyltransferase produced by H gene isα-2-L- fucosyltransferase N-acetyl-D-galactosaminyltransferase D-galactoslytransferaseNone 3. The fucosyltransferase produced by Se gene acts predominantly on disaccharide chains oftype 1type 2type 3type 4 4. The glycosyltransferase produced by A gene isα-2-L- fucosyltransferase N-acetyl-D-galactosaminyltransferaseD-galactoslytransferase None 5. Anti A1 as an alloantibody is seen in serum of A2B individuals with a frequency of1-2%5%10-15%25% 6. Which of the statements are true about anti-A and anti-B? Generally detectable by 3 to 6 months of lifeAnti-A and anti-B in cord blood are of maternal originAdults levels of anti-A and anti-B are reached by 5-10 years of age All of the above are trueOnly A and C are true 7. Anti-H activity is present in the lectin fromDolichos biflorusUlex europeusGlycin sojaNone 8. In a B group individuals, which sugar is present at the site marked with the “?” mark: GalactoseN acetyl galactosamineFructoseSucrose 9. In the proband marked with arrow (see Image 2 on website) safe blood to transfuse is Type ‘O’ PRBCWashed type ‘O’ PRBCWashed Type ‘A1B’ PRBC Bombay phenotype 10. Which of the following statement is/are true about anti-Le antibodiesmajority of these antibodies are IgMthese are of little concern for HDN because newborn red cells are Le(a-b-)in most cases Le antigen negative units are not required for the transfusionAll of the above are correctOnly statement a and c are correct 11. Anti-I isFairly common autoantibody which best react at 37C Seen with infectious mononucleosisSeen with Mycoplasma pneumoniae infection and can cause cold agglutinin diseaseFairly common alloantibody which reacts at 4C 12. Anti-P1 can be neutralized withSalivaHydatid fluidHuman milkPlasma 13. Which of the following statement is true about anti-PP1PkIs an alloantibodySeen in individuals with rare p phenotypeIs cold reactive antibodyIs not capable of hemolysis or hemolytic disease of newborn 14. Antibody associated with paroxysmal cold hemoglobinuria (PCH)Is an alloantibodyIs an biphasic hemolysinIs anti-Le(a)Is anti-PP1Pk(anti-Tja) 15. Antigens of the P system have a receptor for which of the following pathogensUropathogenic E. ColiToxin of enterohemorrhagic E.ColiParvovirus B19All of the aboveOnly B and C are correct Loading...
