PathMD Quizes, Clinical, Hematopathology Peripheral Blood – 04 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. A 60 year old Japanese male presents with abnormal clover-leaf appearing lymphoid cells in the peripheral blood. Flow cytometry is performed. Based on the findings, what is the best diagnosis? Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3Anaplastic large cell lymphomaAngioimmunoblastic T cell lymphomaDiffuse large B-cell lymphomaAdult T cell leukemia/lymphoma Precursor T cell ALL 2. When considering hemoglobin electrophoresis on cellulose acetate at pH 8.4, which of the following is the correct order of Hb migration from the cathode towards the anode?S C F A C S F AS C A F A F S C C S A F 3. Abnormal lymphoid cells are identified in the blood of a 65 year old male. Flow cytometry is performed. Based on the findings, what is the best diagnosis? Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2CLL/SLLPrecursor B Cell ALLMantle Cell Lymphoma Marginal zone lymphomaFollicular Lymphoma – Peripheralized 4. A 45 year old woman presents to the ED with shortness of breath. A CBC was performed and the peripheral blood smear is shown. Based on the findings, what will the patient most likely be found to have? Peripheral Blood - Part 4, Question #4 Peripheral Blood - Part 4, Question #4Anti-i antibody M-spike on SPEPPositive monospot test Anti-I antibodyPositive DAT with IgG and complement 5. The blood smear in this patient comes from a 21 year old male with a mother who has hereditary elliptocytosis. What is the most likely diagnosis? Peripheral Blood - Part 4, Question #5 Peripheral Blood - Part 4, Question #5Microangiopathic hemolytic anemiaThermal injuryDisseminated intravascular coagulation None of the answers are correctHereditary pyropoikilocytosis 6. Tests for hemoglobin solubility are most useful in which of the following situations?Diagnosing sickle cell trait None of the answers are correctDifferentiating a thalassemia from a hemoglobinopathy Distinguishing HbD from HbS Distinguishing HbC(Harlem) from HbS 7. A 3 year old male is found to have “immature” cells in the peripheral blood that are myeloperoxidase negative. Flow cytometry is performed. Based on the findings, what is the best diagnosis? Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1Anaplastic Large Cell Lymphoma Acute myelogenous leukemia with monocytic differentiation None of the answers are correctPrecursor T cell ALLPrecursor B cell ALL 8. The image shown is from a 40 year old female who had a routine CBC, which showed thrombocytopenia (60K). Which of the following best explains her abnormalities? Peripheral Blood - Part 4, Question #6 Peripheral Blood - Part 4, Question #6 Peripheral Blood - Part 4, Question #6May Hegglin Anomaly Acute infection Bernard Soulier DiseaseChediak-Higashi Erhlichia infection Loading...