PathMD Quizes, Hematopathology Gynecological Pathology – 02 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. A 42 y/o female with dysfunctional uterine bleeding is found to have a mass present within the uterine cavity. There is no gross evidence of invasion and does not appear to extend to the lower uterine segment. What is the most likely diagnosis? Gynecological Pathology - Part 2, Case #6 Gynecological Pathology - Part 2, Case #6 Gynecological Pathology - Part 2, Case #6Cervical adenocarcinoma Serous carcinoma Simple hyperplasia Clear cell carcinoma Endometrial Adenocarcinoma 2. A 21-year-old patient is found to have an ovarian mass. A right-sided oophorectomy is performed, and representative histologic images are shown. Based on these findings, which of the following is the best diagnosis? Gynecological Pathology - Part 2, Case #5 Gynecological Pathology - Part 2, Case #5 Gynecological Pathology - Part 2, Case #5 Gynecological Pathology - Part 2, Case #5Granulosa Cell Tumor Yolk sac tumor SeminomaTeratomaDysgerminoma 3. After several months of abnormal bleeding, a 37-year-old female patient presents to her gynecologist for an endometrial biopsy. Representative histologic images of this biopsy are shown. Additional findings not shown include: fragments of unremarkable endometrium adjacent to lesional tissue shown, and areas of morular metaplasia within lesional tissue. Based on these findings, which of the following is the most likely diagnosis? Gynecological Pathology - Part 2, Case #2 Gynecological Pathology - Part 2, Case #2 Gynecological Pathology - Part 2, Case #2Endometrial Polyp Malignant mixed müllerian tumor Endometrial adenocarcinomaAdenofibromaAtypical polypoid adenomyoma 4. Which of the following stains is most often positive in low-grade endometrial stromal sarcomas, and helps differentiate from a cellular leiomyoma?CalretininDesminCD10Ki-67CK5/6 5. A primary uterine serious carcinoma is found to extend from the uterus into the cervix (no cervical stromal invasion) and invades the outer one half of the myometrium. What is the pathologic stage (pT)?pT1bpT1cpT1apT2apT2b 6. A primary ovarian serious carcinoma is present on the surface of the right and left ovaries. Malignant cells are identified in peritoneal washings, but there is no other pelvic extension and/or pelvic implants. What is the pathologic stage (pT)?pT1bpT2apT2bpT1cpT3a 7. A cervical carcinoma is diagnosed at hysterectomy. It is found to extend laterally into the pelvic wall, but does not invade into the uterus or lower third of the vagina. Based on these findings what is the pathologic stage?pT3pT2bpT1pT4pT2a 8. A 45-year-old patient presents to her gynecologist with severe of abdominal cramps. Abdominal ultrasound is suspicious for uterine fibroids. An abdominal hysterectomy is performed, and representative images of a uterine mass found to invade into the outer half of the myometrium is shown. Based on these findings, which of the following is the best diagnosis? Gynecological Pathology - Part 2, Case #3 Gynecological Pathology - Part 2, Case #3 Gynecological Pathology - Part 2, Case #3Stromal noduleCellular leiomyoma LeiomyosarcomaUndifferentiated uterine sarcomaLow-grade endometrial stromal sarcoma 9. A uterine mass is found in a 45-year-old female complaining of severe abdominal cramps for which an abdominal hysterectomy was performed. Gross examination of the uterus showed a single 3 cm nodule in the myometrial wall. Representative histologic images are shown for this case. Immunohistochemistry for CK5/6 is positive in the nucleated cells shown at high power. Based on these findings, which of the following is the best diagnosis? Gynecological Pathology - Part 2, Case #1 Gynecological Pathology - Part 2, Case #1 Gynecological Pathology - Part 2, Case #1Endometrial stromal sarcoma LeiomyomaAdenomatoid tumor AngiomyelolipomaLeiomyosarcoma 10. An ovarian mass found in a 73-year-old patient. An oophorectomy is performed, and representative images of the mass are shown. Based on these findings, which of the following is the best diagnosis? Gynecological Pathology - Part 2, Case #4 Gynecological Pathology - Part 2, Case #4 Gynecological Pathology - Part 2, Case #4Malignant Brenner tumorClear cell carcinomaSertoli Leidig cell tumor DysgerminomaGranulosa cell tumor Loading...