PathMD Quizes, GI Pathology GI Pathology – 05 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Fundic gland polyps are associated with all of the following EXCEPT:H. pylori infectionAdenomatous polyposis coli (APC) gene mutations Proton pump inhibitor therapyFemale gender Familial adenomatous polyposis (FAP) 2. A 60 y/o male presents with a history of chronic diarrhea. Colonoscopy was performed with no significant findings. Random biopsies were obtained, which are shown for this case. Based on these findings, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #1 Gastrointestinal Pathology - Part 5, Question #1Ulcerative colitis Collagenous colitis Lymphocytic colitisBrainerd diarrhea Crohn’s disease 3. All of the following are true about collagenous colitis, EXCEPT:Women outnumber men, 2:1 Increased intraepithelial lymphocytes should always be present Paneth cell metaplasia may indicate treatment resistanceDistal colon biopsies may appear normal The collagen often entraps small capillaries 4. In the images for the case below, which of the following FISH studies would most likely be positive? Endocrine-Exocrine, Question #10 Endocrine-Exocrine, Question #10 Endocrine-Exocrine, Question #10. CD20. Endocrine-Exocrine, Question #10. BCL-1.t(2;5)t(11;14)t(8;14)t(14;18) 5. A 40 y/o female undergoes an EGD. Multiple nodules are noted in the stomach. Based on the images shown, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #4Menetrier’s disease Hyperplastic polyp AdenomaFundic gland polypJuvenile polyp 6. All of the following are characteristic of lymphocytic colitis, EXCEPT:Surface epithelial damage Thickened basement membrane Association with celiac diseaseAssociation with use of ranitidineLamina propria plasmacytosis 7. A 60 y/o man undergoes colonoscopy, and is noted to have a “nodular” mucosal surface. Multiple biopsies are performed, and representative images and stains are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. CD20. Endocrine-Exocrine, Question #9. BCL-1.Marginal zone lymphoma CLL/SLLMantle cell lymphoma Atypical reactive lymphoid hyperplasiaDiffuse large B-cell lymphoma 8. A 36 y/o Mongolian woman presents with disseminated nodule on the peritoneum during an exploratory laporatomy. She has a past history of “stomach cancer” 10 years earlier. Representative images of the histology, including special stains, are shown. What is the best diagnosis? Gastrointestinal Pathology - Part 5 Gastrointestinal Pathology - Part 5 Gastrointestinal Pathology - Part 5. CD34. Gastrointestinal Pathology - Part 5. CD117.Poorly differentiated adenocarcinomaGastrointestinal Stromal Tumor (GIST) Epithelioid hemangioendotheliomaMelanomaLeiomyosarcoma 9. A 64 y/o male presents with chronic weight loss that is significant and unwanted. Chest X-ray and CT scans show infiltrates and a possible mass. The patient has no known history of immune suppression or steroid use. An EGD was performed due to difficulty swallowing and showed a 5cm stricture. This area was biopsied, and representative images are shown. Based on the findings, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #7 Gastrointestinal Pathology - Part 5, Question #7 Gastrointestinal Pathology - Part 5, Question #7MAI infection Invasive fungal infection Poorly differentiated adenocarcinoma TB infection Squamous cell carcinoma 10. Which of the following are true about gastric foveolar polyps?Often have chronic inflammation Are associated with an increased risk of carcinomaTypically occur in the antrum Prominent cystic changeDo not have intestinal metaplasia Loading...