PathMD Quizes, GI Pathology GI Pathology – 05 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. All of the following are true about collagenous colitis, EXCEPT:The collagen often entraps small capillaries Distal colon biopsies may appear normal Increased intraepithelial lymphocytes should always be present Women outnumber men, 2:1 Paneth cell metaplasia may indicate treatment resistance 2. In the images for the case below, which of the following FISH studies would most likely be positive? Endocrine-Exocrine, Question #10 Endocrine-Exocrine, Question #10 Endocrine-Exocrine, Question #10. CD20. Endocrine-Exocrine, Question #10. BCL-1.t(11;14)t(2;5)t(14;18)t(8;14) 3. A 40 y/o female undergoes an EGD. Multiple nodules are noted in the stomach. Based on the images shown, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #4Juvenile polyp Menetrier’s disease AdenomaHyperplastic polyp Fundic gland polyp 4. A 60 y/o male presents with a history of chronic diarrhea. Colonoscopy was performed with no significant findings. Random biopsies were obtained, which are shown for this case. Based on these findings, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #1 Gastrointestinal Pathology - Part 5, Question #1Brainerd diarrhea Lymphocytic colitisCollagenous colitis Ulcerative colitis Crohn’s disease 5. A 60 y/o man undergoes colonoscopy, and is noted to have a “nodular” mucosal surface. Multiple biopsies are performed, and representative images and stains are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. CD20. Endocrine-Exocrine, Question #9. BCL-1.Marginal zone lymphoma Atypical reactive lymphoid hyperplasiaMantle cell lymphoma CLL/SLLDiffuse large B-cell lymphoma 6. Fundic gland polyps are associated with all of the following EXCEPT:Adenomatous polyposis coli (APC) gene mutations Proton pump inhibitor therapyFamilial adenomatous polyposis (FAP) H. pylori infectionFemale gender 7. All of the following are characteristic of lymphocytic colitis, EXCEPT:Association with use of ranitidineSurface epithelial damage Association with celiac diseaseLamina propria plasmacytosis Thickened basement membrane 8. A 36 y/o Mongolian woman presents with disseminated nodule on the peritoneum during an exploratory laporatomy. She has a past history of “stomach cancer” 10 years earlier. Representative images of the histology, including special stains, are shown. What is the best diagnosis? Gastrointestinal Pathology - Part 5 Gastrointestinal Pathology - Part 5 Gastrointestinal Pathology - Part 5. CD34. Gastrointestinal Pathology - Part 5. CD117.MelanomaEpithelioid hemangioendotheliomaLeiomyosarcomaGastrointestinal Stromal Tumor (GIST) Poorly differentiated adenocarcinoma 9. Which of the following are true about gastric foveolar polyps?Are associated with an increased risk of carcinomaDo not have intestinal metaplasiaTypically occur in the antrum Prominent cystic changeOften have chronic inflammation 10. A 64 y/o male presents with chronic weight loss that is significant and unwanted. Chest X-ray and CT scans show infiltrates and a possible mass. The patient has no known history of immune suppression or steroid use. An EGD was performed due to difficulty swallowing and showed a 5cm stricture. This area was biopsied, and representative images are shown. Based on the findings, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #7 Gastrointestinal Pathology - Part 5, Question #7 Gastrointestinal Pathology - Part 5, Question #7Squamous cell carcinoma MAI infection Invasive fungal infection TB infection Poorly differentiated adenocarcinoma Loading...