PathMD Quizes, Clinical, Head & Neck Thyroid October 29, 2017 peferguson Author: Max Llaudes, M.D. & Joshua Bornhorst, Ph.D. Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. A 34 year old female with history of hypothyroidism controlled with l-thyroxine comes to the office for her 8-week prenatal check-up. Her vital signs and physical examination are non-contributory. What is the appropriate management of the hypothyroidism in this patient?Decrease the dose of L-thyroxineMeasure the T4 concentrationDiscontinue L-thyroxineObservation and thyroid studies at 24 weeksIncrease the dose of L-thyroxine 2. In the presence of a TSH secreting pituitary tumorFree T3 increasesHypothyroidism results due to hypothalamic suppression effectFree T4 decreasesThe radioactive iodine uptake decreasesThyroglobulin decreases 3. Which of the following conditions does not usually result in hypothyrodism?Subacute granulomatous thyroiditisUse of radioactive iodine for the treatment of Grave’s diseaseAutoimmune thyroiditisAll of the above conditions may result in hypothyroidismPostpartum thyroiditis 4. Which of the following conditions will present with a reduced radioactive iodine uptakePost-partum thyroiditisIodine-induced thyrotoxicosisAmiodarone-induced thyrotoxicosisPainless thyroiditisAll of the above will result in a reduced uptake of radioactive iodine 5. In Grave’s diseaseThyroid Stimulating Immunoglobulins (TSI) are present in serumThe free thyroid is lowThe thyroid gland shows nodular “hot” noduleThe radioiodine uptake is low 6. Which is the best indicator of thyroxine abuse?Radioactive Iodine uptakeTSH levelThyroglobulin level Anti-thyroid peroxidase levelUltrasound of the thyroid 7. Which of the following statements regarding the biological effects of thyroid hormone is correct?A cellular transmembrane tyrosine kinase receptor mediates the biological effects of thyroid hormoneTheir biological effects are mediated by interactions between the hormone and cell membrane receptorsNone of the above statements is correctThe thyroid hormone water solubility allows to permeate through the cell membrane and bind intranuclear protein receptorsThe thyroid hormone receptors are free intracellular proteins with high specificity and affinity for thyroid hormone binding sites 8. Which of the following statements regarding Euthyroid sick syndrome is correctResults in an increase in the peripheral conversion of T4 to T3Anti-thyroglobulin is present in high concentrationsCauses a marked elevation of TSH levelsThe levels of Free T4 are normal in moderate illness 9. Which of the following is not a feature of Autoimmune Hashimoto thyroiditisAnti-thyroid peroxidase antibodiesAnti-thyroglobulin antibodiesAntibodies to the TSH receptorIt may present as an enlarging thyroid gland 10. Which of the following statements regarding the management of hypothyroid patients during pregnancy is correct?Thyroxine requirements decrease due to transient hyperthyroidism of pregnancyContinue the same dose of L-thyroxineThyroxine therapy needs to be discontinuedNone of the above statements is correctThyroid hormone free levels increase during pregnancy Loading...