PathMD Quizes, Clinical, Head & Neck Thyroid October 29, 2017 peferguson Author: Max Llaudes, M.D. & Joshua Bornhorst, Ph.D. Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Which of the following statements regarding Euthyroid sick syndrome is correctThe levels of Free T4 are normal in moderate illnessResults in an increase in the peripheral conversion of T4 to T3Anti-thyroglobulin is present in high concentrationsCauses a marked elevation of TSH levels 2. In Grave’s diseaseThe free thyroid is lowThyroid Stimulating Immunoglobulins (TSI) are present in serumThe radioiodine uptake is lowThe thyroid gland shows nodular “hot” nodule 3. A 34 year old female with history of hypothyroidism controlled with l-thyroxine comes to the office for her 8-week prenatal check-up. Her vital signs and physical examination are non-contributory. What is the appropriate management of the hypothyroidism in this patient?Decrease the dose of L-thyroxineDiscontinue L-thyroxineIncrease the dose of L-thyroxineMeasure the T4 concentrationObservation and thyroid studies at 24 weeks 4. Which of the following is not a feature of Autoimmune Hashimoto thyroiditisIt may present as an enlarging thyroid glandAntibodies to the TSH receptorAnti-thyroglobulin antibodiesAnti-thyroid peroxidase antibodies 5. Which is the best indicator of thyroxine abuse?Thyroglobulin level Radioactive Iodine uptakeTSH levelAnti-thyroid peroxidase levelUltrasound of the thyroid 6. Which of the following conditions will present with a reduced radioactive iodine uptakePainless thyroiditisIodine-induced thyrotoxicosisAmiodarone-induced thyrotoxicosisAll of the above will result in a reduced uptake of radioactive iodinePost-partum thyroiditis 7. Which of the following conditions does not usually result in hypothyrodism?Subacute granulomatous thyroiditisAutoimmune thyroiditisUse of radioactive iodine for the treatment of Grave’s diseasePostpartum thyroiditisAll of the above conditions may result in hypothyroidism 8. Which of the following statements regarding the management of hypothyroid patients during pregnancy is correct?Thyroxine requirements decrease due to transient hyperthyroidism of pregnancyContinue the same dose of L-thyroxineThyroxine therapy needs to be discontinuedThyroid hormone free levels increase during pregnancyNone of the above statements is correct 9. Which of the following statements regarding the biological effects of thyroid hormone is correct?The thyroid hormone receptors are free intracellular proteins with high specificity and affinity for thyroid hormone binding sitesThe thyroid hormone water solubility allows to permeate through the cell membrane and bind intranuclear protein receptorsA cellular transmembrane tyrosine kinase receptor mediates the biological effects of thyroid hormoneTheir biological effects are mediated by interactions between the hormone and cell membrane receptorsNone of the above statements is correct 10. In the presence of a TSH secreting pituitary tumorFree T3 increasesThe radioactive iodine uptake decreasesHypothyroidism results due to hypothalamic suppression effectFree T4 decreasesThyroglobulin decreases Loading...
