PathMD Quizes, Lung Lung – 03 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Approximately what percentage of cases of newly diagnosed lung cancer occur in heavy smokers (or those who recently quit)?40%25%80%60%>95% 2. Gain of function mutations (e.g. tyrosine kinase mutations) in lung cancer are most commonly associated with which of the following subtypes:Squamous Cell CarcinomaSmall Cell CarcinomaAdenocarcinomaLarge Cell CarcinomaCarcinoid 3. Which of the following is least helpful in differentiating between a typical and atypical carcinoid?Presence of lymphatic invasionPresence of necrosisGrowth patternTumor sizeMitotic index 4. Which of the following activating mutations is NOT associated with a response to targeted therapy (e.g. tyrosine kinase inhibitors)?EGFRKRASc-METROS-1ALK 5. As part of the manifestation of paraneoplastic syndromes, ADH is most commonly associated with what lung carcinoma subtype?Squamous Cell CarcinomaLarge Cell Neuroendocrine CarcinomaLarge Cell CarcinomaSmall Cell CarcinomaAdenocarcinoma 6. Adenocarcinoma in situ of the lung should not have evidence of invasion, and should be less than:3 cm1 cm1.5 cm0.5 cm2 cm Loading...