Angioimmunoblastic T-Cell Lymphoma

Immunophenotypic Expression Pattern
Marker
Comment
Positive
Positive
Positive
Positive
Positive
Positive (often numerous reactive T-cells will be present)
Positive in the neoplastic cells in ~50% of cases
CXCL13
Positive in a majority of cases (marker of follicular helper T-cells)
EBV (EBER)
Positive in reactive B-cells
Negative
Expanded FDC network
It is not uncommon for some of the T-cell markers to be dropped.
References
Parker, A., et. al.  “Best Practice in Lymphoma Diagnosis and Reporting.”  British Committee for Standards in Haematology, Royal College of Pathologists.  April, 2010.