Introductal papilloma can have varying appearances but characteristically contain an ductal epithelial proliferation on a fibrovascular core with an intact myoepithelial layer.  Larger duct lesions are located near the nipple and typically produce a discharge (~80%).  Small duct lesions are frequently multiple and located deeper in the breast.

 

Papilloma are are associated with a slight increased risk for breast carcinoma (1.5-2x increased relative risk).  The absence of a myoepithelial layer is not characteristic of a typical papilloma, and likely represents a different papillary lesion.