Breast Lesions and Risk of Developing an Invasive Carcinoma

The following table and figure illustrate the risk of developing an invasive breast carcinoma based on the type of lesions previously identified. This information does not take into consideration other factors such as race and family history (complicated topic).

Relative and Absolute Risk of Invasive Breast Carcinoma

Relative Risk	Absolute Risk (lifetime)	Breast Lesion
1	3%	Fibroadenoma Duct ectasia Mild usual hyperplasia Fibrocystic change Adenosis
1.5 – 2	5-7%	Moderate to florid usual hyperplasia Radial scar (complex sclerosing lesion) Papilloma Sclerosing adenosis
4 – 5	13-17%	Atypical ductal hyperplasia (ADH) Atypical lobular hyperplasia (ALH)
8 – 10	25-30%	Ductal Carcinoma In Situ (DCIS) Lobular Carcinoma In Situ (LCIS)

References

Kumar, Vinay, Abul K. Abbas, and Jon C. Aster. Robbins and Cotran Pathologic Basis of Disease. Ninth edition. Philadelphia, PA: Elsevier/Saunders, 2015.