Immunohistochemistry
Positive
|
|
Positive
|
|
34BE12
|
Positive
|
Positive
|
|
Usually negative (<20% +)
|
|
Negative
|
There is evidence that CD5 may be used to differentiate thymic carcinomas (+) from esophageal SCC (-), but this is dependent upon the antibody clone used and the antigen retrieval method. Otherwise, both may stain. Use of CD5 in this setting would not be advised unless one’s laboratory has specifically validated the antibody for this differential diagnosis.