PathMD Quizes, Clinical, Hematopathology Coagulation – 01 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. The PFA-100 analyzer has replaced the bleeding time at many institutions. This test utilizes two tubes for analysis. One tube contains collagen and ADP, while the other tube has collagen epinephrine. In a patient who has a prolonged bleeding time, which of the following would have a normal clotting time in the collagen and ADP tube but be prolonged and the collagen epinephrine tube?All the answers will affect both tubes Bernard-Soulier disease Von Willebrand's disease Aspirin effectThrombocytopenia 2. A patient underwent cardiac bypass surgery and was having an uneventful post-operative course. On POD #7, the patient developed an ischemic leg. The intern asks your help in diagnosis, and also informs you that his platelet count has recently dropped. The most likely etiology is:DVT with paradoxical embolusHyperhomocystinemiaIdiopathic Thrombocytopenia purpuraHeparin induced thrombocytopeniaThrombotic thrombocytopenia 3. Which of the following would be least helpful in treating a patient with hemophilia A:CryoprecipitateRecombinant factor VIIIDDAVPAll of the answers would be helpfulFFP 4. Adhesion of platelets is mediated through all of the following EXCEPT:GPIIb/IIIaGPIbCollagenvon Willebrand's factor 5. The image for this question shown on the website represents initial platelet adhesion to the vessel wall and aggregation. What structure is represented by the red box in the image? Coagulation - Part 1, Question #2GPIIb/IIIa receptor GPIb receptor FibrinogenVon Willebrands factor Collagen 6. A patient who is known to have von Willebrand’s disease (vWD) has a normal vWF antigen and decreased levels of Factor VIII. What is the most likely vWD subtype in this patient?vWD, type 2N vWD, type 2B vWD, type 2A vWD, type 2M Platelet type, pseudo-von Willebrand’s disease 7. The image for this question shown on the website represents initial platelet adhesion to the vessel wall and aggregation. What structure is represented by the red box in the image? Coagulation - Part 1, Question #1CollagenFibrinogenGPIb receptor Von Willebrands factor GPIIb/IIIa receptor 8. Moderate hemophilia A is characterized by which of the following approximated factor VIII levels:<1%1-5% 5-10%>20%10-20% 9. A patient underwent cardiac bypass surgery and was having an uneventful post-operative course. On POD #7, the patient developed an ischemic leg. The intern asks your help in diagnosis, and also informs you that his platelet count has recently dropped. Which of the following tests would be most helpful in diagnosing the patient?ADAM-TS level Heparin antibody Methyltetrahydrofolate reductase mutationQualitative d-dimer Quantitative d-dimer 10. A patient is suspected of having Bernard-Soulier disease. If the patient has this disease, they would show response to all of the following during platelet testing EXCEPT:EpinephrineRistocetinADPThromboxane A2Collagen Loading...