PathMD Quizes, Anatomic Electron Microscopy – 01 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. EM of a CNS tumor showed intracellular lumens lined by microvilli with specialized junctions between cells and glial features. This is most conisistant with which of the following tumors:CarcinomaSchwannomaChoroid plexus tumorAstrocytomaEpendymoma 2. A specimen being prepared for electron microscopy should be fixed in:Zinc formalin B5Mercury based fixativeGluteraldehydeBouin’s 3. Based on the findings in the images below for Case #2, which of the following is the best diagnosis? Electron Microscopy Set 1 Case 2 Electron Microscopy Set 1 Case 2PlasmacytomaMelanomaAdenocarcinomaSchwannomaGranular Cell Tumor 4. Based on the findings in the images below for Case #4, which of the following is the best diagnosis? Electron Microscopy Set 1 Case 4 Electron Microscopy Set 1 Case 4AdenocarcinomaSchwannomaSquamous Cell Carcinoma MeningiomaLymphoma 5. Based on the findings in the images below for Case 1, which of the following is the best diagnosis? Electron Microscopy Set 1 Case 1 Electron Microscopy Set 1 Case 1 Electron Microscopy Set 1 Case 1AdenocarcinomaSquamous Cell Carcinoma SchwannomaMelanomaMesothelioma 6. Based on the findings in the image below for Case #5, which of the following is the best diagnosis? Electron Microscopy Set 1 Case 5OncocytomaRenal Cell Carcinoma, clear cell typeMelanomaRenal Cell Carcinoma, chromophobe type Granular Cell Tumor 7. Based on the findings in the images below for Case #3, which of the following is the best diagnosis? Electron Microscopy Set 1 Case 3 Electron Microscopy Set 1 Case 3SchwannomaMesotheliomaMelanomaAdenocarcinomaSquamous Cell Carcinoma 8. EM of a CNS tumor shows prominent interdigitating processes without a basal lamina. There are well formed desmosome junctions and prominent cytoplasmic inclusions. These findings are most consistent with:LymphomaCarcinomaMeningiomaSchwannomaEpendymoma 9. EM of an undifferentiated tumor shows microvilli with long filamentous core rootlets (electron dense). This finding suggests which diagnosis:GI adenocarcinoma Breast adenocarcinoma Thyroid follicular carcinoma MesotheliomaProstate carcinoma 10. A biopsy from the tongue shows pseudoepitheliomatous hyperplasia with histiocyte like cells underneath, which contain a granular cytoplasm. A diagnosis is suspected and confirmed with S-100 positivity. Which of the following is true with regards to this tumor:EM will show numerous lysosomesEM will show abundant mitochondria EM will show cytoplasmic microvilli EM will show abundant rough endoplasmic reticulum EM will show numerous premelanosomes 11. EM of a tumor shows rhomboid crystalline inclusions. Cytogenetics also showed a t(X;17). These findings are consistent with which of the following neoplasms?MedulloblastomaPapillary ependymoma NeurocytomaClear cell sarcomaAlveolar soft part sarcoma 12. EM of an undifferentiated tumor is noted to have long thin microvilli (height to width ~ 10:1). Which of the following tumors is this most consistent with:MesotheliomaProstate carcinoma Thyroid follicular carcinoma Breast adenocarcinoma Pulmonary adenocarcinoma 13. An undifferentiated tumor shows prominent profiles of rough endoplasmic reticulum. Which of the following markers would also be positive in this lesion?CD138CD45S-100 Hale’s colloidal ironSynaptophysin Loading...