PathMD Quizes, Clinical Endocrine Pathology – 01 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. What is the fatality rate for widely invasive follicular carcinoma tumors?75%25%>90%3%50% 2. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation. Based on the histology and special stains, what is the best diagnosis? Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7. AE1/AE3 Endocrine-Exocrine, Question #7. CD34 Endocrine-Exocrine, Question #7. PASEpithelioid angiosarcomaAcinar cell cystadenomaLymphangiomaMicrocystic serous cystadenomaPancreatic pseudocyst 3. All of the following are true with respect to follicular thyroid carcinoma EXCEPT:Radiation exposure is a risk factorMicroinvasive follicular carcinomas have an excellent prognosisRepresent ~5% of thyroid cancersHigher incidence in iodine deficient areasPropensity for lymphatic invasion 4. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown. The patient in the above case was found to have a gastric stromal sarcoma. In light of the new findings, what is the best clinical diagnosis for this patient? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. SynaptophysinCarneyʼs syndromeNone of the answers are correctMultiple endocrine neoplasiaVon Hippel-Lindau diseaseCarneyʼs triad 5. In mantle cell lymphoma, which of the following FISH studies would most likely be positive?t(14;18)t(8;14)t(11;14)t(2;5) 6. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation. This entity can be associated with all of the following EXCEPT: Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7. AE1/AE3 Endocrine-Exocrine, Question #7. CD34 Endocrine-Exocrine, Question #7. PASDuctal adenocarcinoma of the pancreasMultiple endocrine neoplasiaDiabetesVon Hippel-Lindau disease 7. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. Chromogranin Endocrine-Exocrine, Question #9. SynaptophysinMyelolipomaAdrenal cortical adenomaPheochromocytomaAdrenal carcinoma 8. A 50 y/o male presents with an enlarged thyroid. Due to the mass effect, a complete thyroidectomy is performed. Based on the images shown, what is the best diagnosis? Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1Adenomatoid nodulesNodular hyperplasiaFollicular carcinomaFollicular variant of papillary carcinomaFollicular adenoma 9. A 60 y/o man undergoes colonoscopy, and is noted to have a “nodular” mucosal surface. Multiple biopsies are performed, and representative images and stains are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5. CD3. Endocrine-Exocrine, Question #5. CD5. Endocrine-Exocrine, Question #5. CD20. Endocrine-Exocrine, Question #5. BCL-1. Endocrine-Exocrine, Question #5. BCL-2.Diffuse large B-cell lymphomaAtypical reactive lymphoid hyperplasiaMarginal zone lymphomaMantle cell lymphomaCLL/SLL 10. Where in the normal thyroid gland are C-cells found in the highest concentration?Lower poleIsthmusUpper poleMiddle portion Loading...