Endocrine Pathology – 01

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1. A 50 y/o male presents with an enlarged thyroid. Due to the mass effect, a complete thyroidectomy is performed. Based on the images shown, what is the best diagnosis?

Endocrine-Exocrine, Question #1
Endocrine-Exocrine, Question #1


Endocrine-Exocrine, Question #1
Endocrine-Exocrine, Question #1


Endocrine-Exocrine, Question #1
Endocrine-Exocrine, Question #1


Endocrine-Exocrine, Question #1
Endocrine-Exocrine, Question #1
2. Where in the normal thyroid gland are C-cells found in the highest concentration?
3. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation.  This entity can be associated with all of the following EXCEPT:

Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7


Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7


Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7. AE1/AE3


Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7. CD34


Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7. PAS
4. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown.

The patient in the above case was found to have a gastric stromal sarcoma. In light of the new findings, what is the best clinical diagnosis for this patient?

Endocrine-Exocrine, Question #9
Endocrine-Exocrine, Question #9


Endocrine-Exocrine, Question #9
Endocrine-Exocrine, Question #9


Endocrine-Exocrine, Question #9
Endocrine-Exocrine, Question #9


Endocrine-Exocrine, Question #9
Endocrine-Exocrine, Question #9. Synaptophysin
5. All of the following are true with respect to follicular thyroid carcinoma EXCEPT:
6. What is the fatality rate for widely invasive follicular carcinoma tumors?
7. A 60 y/o man undergoes colonoscopy, and is noted to have a “nodular” mucosal surface. Multiple biopsies are performed, and representative images and stains are shown. Based on the findings, what is the best diagnosis?

Endocrine-Exocrine, Question #5
Endocrine-Exocrine, Question #5


Endocrine-Exocrine, Question #5
Endocrine-Exocrine, Question #5


Endocrine-Exocrine, Question #5
Endocrine-Exocrine, Question #5


Endocrine-Exocrine, Question #5
Endocrine-Exocrine, Question #5. CD3.


Endocrine-Exocrine, Question #5
Endocrine-Exocrine, Question #5. CD5.


Endocrine-Exocrine, Question #5
Endocrine-Exocrine, Question #5. CD20.


Endocrine-Exocrine, Question #5. BCL-1.


Endocrine-Exocrine, Question #5
Endocrine-Exocrine, Question #5. BCL-2.
8. In mantle cell lymphoma, which of the following FISH studies would most likely be positive?
9. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown. Based on the findings, what is the best diagnosis?

Endocrine-Exocrine, Question #9
Endocrine-Exocrine, Question #9


Endocrine-Exocrine, Question #9
Endocrine-Exocrine, Question #9


Endocrine-Exocrine, Question #9
Endocrine-Exocrine, Question #9


Endocrine-Exocrine, Question #9
Endocrine-Exocrine, Question #9. Chromogranin


Endocrine-Exocrine, Question #9
Endocrine-Exocrine, Question #9. Synaptophysin
10. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation. Based on the histology and special stains, what is the best diagnosis?

Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7


Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7


Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7


Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7


Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7. AE1/AE3


Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7. CD34


Endocrine-Exocrine, Question #7
Endocrine-Exocrine, Question #7. PAS