PathMD Quizes, Clinical Endocrine Pathology – 01 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. A 50 y/o male presents with an enlarged thyroid. Due to the mass effect, a complete thyroidectomy is performed. Based on the images shown, what is the best diagnosis? Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1Follicular variant of papillary carcinomaNodular hyperplasiaAdenomatoid nodulesFollicular adenomaFollicular carcinoma 2. Where in the normal thyroid gland are C-cells found in the highest concentration?Middle portionUpper poleIsthmusLower pole 3. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation. This entity can be associated with all of the following EXCEPT: Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7. AE1/AE3 Endocrine-Exocrine, Question #7. CD34 Endocrine-Exocrine, Question #7. PASDiabetesVon Hippel-Lindau diseaseMultiple endocrine neoplasiaDuctal adenocarcinoma of the pancreas 4. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown. The patient in the above case was found to have a gastric stromal sarcoma. In light of the new findings, what is the best clinical diagnosis for this patient? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. SynaptophysinVon Hippel-Lindau diseaseCarneyʼs syndromeNone of the answers are correctMultiple endocrine neoplasiaCarneyʼs triad 5. All of the following are true with respect to follicular thyroid carcinoma EXCEPT:Represent ~5% of thyroid cancersHigher incidence in iodine deficient areasRadiation exposure is a risk factorMicroinvasive follicular carcinomas have an excellent prognosisPropensity for lymphatic invasion 6. What is the fatality rate for widely invasive follicular carcinoma tumors?3%>90%75%50%25% 7. A 60 y/o man undergoes colonoscopy, and is noted to have a “nodular” mucosal surface. Multiple biopsies are performed, and representative images and stains are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5. CD3. Endocrine-Exocrine, Question #5. CD5. Endocrine-Exocrine, Question #5. CD20. Endocrine-Exocrine, Question #5. BCL-1. Endocrine-Exocrine, Question #5. BCL-2.Diffuse large B-cell lymphomaMantle cell lymphomaAtypical reactive lymphoid hyperplasiaCLL/SLLMarginal zone lymphoma 8. In mantle cell lymphoma, which of the following FISH studies would most likely be positive?t(2;5)t(14;18)t(8;14)t(11;14) 9. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. Chromogranin Endocrine-Exocrine, Question #9. SynaptophysinPheochromocytomaAdrenal carcinomaMyelolipomaAdrenal cortical adenoma 10. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation. Based on the histology and special stains, what is the best diagnosis? Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7. AE1/AE3 Endocrine-Exocrine, Question #7. CD34 Endocrine-Exocrine, Question #7. PASMicrocystic serous cystadenomaEpithelioid angiosarcomaAcinar cell cystadenomaLymphangiomaPancreatic pseudocyst Loading...