The International Federation of Gynecology and Obstetrics (FIGO) grading system for endometrial endometrioid carcinoma:
- FIGO Grade 1: <=5% solid, non-glandular, non-squamous growth
- FIGO Grade 2: 6-50% solid, non-glandular, non-squamous growth
- FIGO Grade 3: >50% solid, non-glandular, non-squamous growth
Marked cytologic atypia increases the grade by 1.
FIGO Grading is only performed on endometrioid and mucinous adenocarinomas. Other tumor subtypes (clear cell, serous, carcinomasarcomas) carry their own associated grade. Mucinous adenocarcinomas are considered to be closely related to endometrioid carcinomas.
References
- Soslow RA, Tornos C, Park KJ, Malpica A, Matias-Guiu X, Oliva E, et al. Endometrial Carcinoma Diagnosis: Use of FIGO Grading and Genomic Subcategories in Clinical Practice: Recommendations of the International Society of Gynecological Pathologists. Int J Gynecol Pathol. 2019;38 Suppl 1: S64–S74. doi:10.1097/PGP.0000000000000518