PathMD Quizes, GI Pathology GI Pathology – 05 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. A 64 y/o male presents with chronic weight loss that is significant and unwanted. Chest X-ray and CT scans show infiltrates and a possible mass. The patient has no known history of immune suppression or steroid use. An EGD was performed due to difficulty swallowing and showed a 5cm stricture. This area was biopsied, and representative images are shown. Based on the findings, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #7 Gastrointestinal Pathology - Part 5, Question #7 Gastrointestinal Pathology - Part 5, Question #7Squamous cell carcinoma MAI infection TB infection Poorly differentiated adenocarcinoma Invasive fungal infection 2. In the images for the case below, which of the following FISH studies would most likely be positive? Endocrine-Exocrine, Question #10 Endocrine-Exocrine, Question #10 Endocrine-Exocrine, Question #10. CD20. Endocrine-Exocrine, Question #10. BCL-1.t(11;14)t(14;18)t(8;14)t(2;5) 3. A 40 y/o female undergoes an EGD. Multiple nodules are noted in the stomach. Based on the images shown, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #4Menetrier’s disease Hyperplastic polyp Juvenile polyp AdenomaFundic gland polyp 4. Which of the following are true about gastric foveolar polyps?Often have chronic inflammation Typically occur in the antrum Prominent cystic changeDo not have intestinal metaplasiaAre associated with an increased risk of carcinoma 5. A 60 y/o man undergoes colonoscopy, and is noted to have a “nodular” mucosal surface. Multiple biopsies are performed, and representative images and stains are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. CD20. Endocrine-Exocrine, Question #9. BCL-1.CLL/SLLAtypical reactive lymphoid hyperplasiaMarginal zone lymphoma Diffuse large B-cell lymphoma Mantle cell lymphoma 6. A 36 y/o Mongolian woman presents with disseminated nodule on the peritoneum during an exploratory laporatomy. She has a past history of “stomach cancer” 10 years earlier. Representative images of the histology, including special stains, are shown. What is the best diagnosis? Gastrointestinal Pathology - Part 5 Gastrointestinal Pathology - Part 5 Gastrointestinal Pathology - Part 5. CD34. Gastrointestinal Pathology - Part 5. CD117.Gastrointestinal Stromal Tumor (GIST) Epithelioid hemangioendotheliomaLeiomyosarcomaPoorly differentiated adenocarcinomaMelanoma 7. Fundic gland polyps are associated with all of the following EXCEPT:Adenomatous polyposis coli (APC) gene mutations Female gender H. pylori infectionProton pump inhibitor therapyFamilial adenomatous polyposis (FAP) 8. All of the following are characteristic of lymphocytic colitis, EXCEPT:Lamina propria plasmacytosis Association with use of ranitidineSurface epithelial damage Thickened basement membrane Association with celiac disease 9. All of the following are true about collagenous colitis, EXCEPT:Paneth cell metaplasia may indicate treatment resistanceThe collagen often entraps small capillaries Women outnumber men, 2:1 Increased intraepithelial lymphocytes should always be present Distal colon biopsies may appear normal 10. A 60 y/o male presents with a history of chronic diarrhea. Colonoscopy was performed with no significant findings. Random biopsies were obtained, which are shown for this case. Based on these findings, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #1 Gastrointestinal Pathology - Part 5, Question #1Ulcerative colitis Lymphocytic colitisCollagenous colitis Crohn’s diseaseBrainerd diarrhea Loading...