PathMD Quizes, GI Pathology GI Pathology – 05 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Fundic gland polyps are associated with all of the following EXCEPT:Adenomatous polyposis coli (APC) gene mutations Familial adenomatous polyposis (FAP) H. pylori infectionFemale gender Proton pump inhibitor therapy 2. A 60 y/o man undergoes colonoscopy, and is noted to have a “nodular” mucosal surface. Multiple biopsies are performed, and representative images and stains are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. CD20. Endocrine-Exocrine, Question #9. BCL-1.Mantle cell lymphoma Atypical reactive lymphoid hyperplasiaDiffuse large B-cell lymphoma CLL/SLLMarginal zone lymphoma 3. A 64 y/o male presents with chronic weight loss that is significant and unwanted. Chest X-ray and CT scans show infiltrates and a possible mass. The patient has no known history of immune suppression or steroid use. An EGD was performed due to difficulty swallowing and showed a 5cm stricture. This area was biopsied, and representative images are shown. Based on the findings, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #7 Gastrointestinal Pathology - Part 5, Question #7 Gastrointestinal Pathology - Part 5, Question #7Squamous cell carcinoma Invasive fungal infection Poorly differentiated adenocarcinoma MAI infection TB infection 4. All of the following are characteristic of lymphocytic colitis, EXCEPT:Association with celiac diseaseThickened basement membrane Lamina propria plasmacytosis Association with use of ranitidineSurface epithelial damage 5. A 36 y/o Mongolian woman presents with disseminated nodule on the peritoneum during an exploratory laporatomy. She has a past history of “stomach cancer” 10 years earlier. Representative images of the histology, including special stains, are shown. What is the best diagnosis? Gastrointestinal Pathology - Part 5 Gastrointestinal Pathology - Part 5 Gastrointestinal Pathology - Part 5. CD34. Gastrointestinal Pathology - Part 5. CD117.Gastrointestinal Stromal Tumor (GIST) LeiomyosarcomaEpithelioid hemangioendotheliomaPoorly differentiated adenocarcinomaMelanoma 6. A 60 y/o male presents with a history of chronic diarrhea. Colonoscopy was performed with no significant findings. Random biopsies were obtained, which are shown for this case. Based on these findings, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #1 Gastrointestinal Pathology - Part 5, Question #1Collagenous colitis Brainerd diarrhea Lymphocytic colitisUlcerative colitis Crohn’s disease 7. A 40 y/o female undergoes an EGD. Multiple nodules are noted in the stomach. Based on the images shown, what is the best diagnosis? Gastrointestinal Pathology - Part 5, Question #4Menetrier’s disease Hyperplastic polyp AdenomaJuvenile polyp Fundic gland polyp 8. Which of the following are true about gastric foveolar polyps?Do not have intestinal metaplasiaTypically occur in the antrum Prominent cystic changeAre associated with an increased risk of carcinomaOften have chronic inflammation 9. All of the following are true about collagenous colitis, EXCEPT:Women outnumber men, 2:1 Distal colon biopsies may appear normal The collagen often entraps small capillaries Increased intraepithelial lymphocytes should always be present Paneth cell metaplasia may indicate treatment resistance 10. In the images for the case below, which of the following FISH studies would most likely be positive? Endocrine-Exocrine, Question #10 Endocrine-Exocrine, Question #10 Endocrine-Exocrine, Question #10. CD20. Endocrine-Exocrine, Question #10. BCL-1.t(14;18)t(2;5)t(8;14)t(11;14) Loading...