1.

The cell pictured from a blood smear best represents, which of the following:

2. A 13 y/o girl presents with cervical adenopathy. A lymph node biopsy was performed and representative images are shown. Based on the findings, the best answer is:

3. A biopsy of a lymph node from a 30 y/o shows multiple foci of pigment throughout the lymph node which is represented in the image for this case. Upon close examination under high power, it does not appear to be intracellular. The lymph node otherwise appeared reactive. What is the most likely etiology?

4. A lymph node is composed of large, expanded, irregularly shaped follicles (some of which form giant geographic structures). The interfollicular areas have plasma cells, histiocytes, and monocytoid B-cells. This description best describes which of the following entities:

5. The image for this case is from a lymph node in a 21 y/o male with a known history of Hodgkin’s lymphoma. With regard to the large cell of interest (pictured), all of the following are true EXCEPT:

6. Which one of the following stains would be most helpful in differentiating a reactive and neoplastic lymph node:

7. HHV-8 is associated with all of the following EXCEPT:

8. A 45 y/o man presents with axillary adenopathy. A biopsy was performed and a representative image of the lymph node is shown. Immunohistochemistry showed the cells to be positive for EMA and CD30. CD20 and CD15 were negative. Based on these findings, the best answer is:

9. Which of the following is not part of the WHO’s classification of acute myeloid leukemia with recurring genetic abnormalities?

10. The blood smear pictured from this case is from a 30 year old female with a history of travel to Africa 1 month ago and cyclic fevers every 48 hours. The RBCs pictured are normal in size. Based on the findings, the best diagnosis is: