PathMD Quizes, Hematopathology Hematopathology – 05 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. A patient presents with an elevated WBC count, and flow cytometry is performed. Based on the dot plots shown the website images for this case, what is the best diagnosis? Hematopathology - Part 5, Case #2 Hematopathology - Part 5, Case #2 Hematopathology - Part 5, Case #2 Hematopathology - Part 5, Case #2 Hematopathology - Part 5, Case #2 Hematopathology - Part 5, Case #2Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaT-cell ALL B-cell ALL Peripheralized Marginal Zone LymphomaMantle cell lymphoma 2. A 40 year old woman presents with an elevated WBC count (25K) with abnormal immature cells noted by the hematology technologist (see case images). Flow cytometry demonstrated the cells to be positive for CD13 and CD33 and negative for CD34 and HLA-DR. What is the best diagnosis? Hematopathology - Part 5, Case #3 Hematopathology - Part 5, Case #3 Hematopathology - Part 5, Case #3 Hematopathology - Part 5, Case #3. Myeloperoxidase (MPO).AML-M2AML-M0APLAML-M4B-ALL 3. A 36 year old Hispanic male with a CD4 count of 20 presents to the emergency department complaining of chronic headaches for several months. A routine CBC showed pancytopenia, and a bone marrow biopsy was performed. Based on the findings, what is the most likely diagnosis? Hematopathology - Part 5, Case #4 Hematopathology - Part 5, Case #4 Hematopathology - Part 5, Case #4 Hematopathology - Part 5, Case #4. GMS stain.BlastomycosisCoccidiomycosisHistoplasmosisMycobacterium avium Cryptococcus 4. A patient with a history of acute leukemia undergoes a bone marrow aspiration. Part of the specimen is sent for cytogenetic analysis. Results of the karyotype are shown in the image for this case. Based on the findings (which are highlighted by red arrows), what is the best diagnosis? Hematopathology - Part 5, Case #5ALLAML-M2 AML-M4EoAML-M5aAML-M3 5. All of the following are true with respect to MALT/marginal zone lymphomas EXCEPT:Trisomy 3 in a majority of MALT cases None of the answers are incorrectt(11;18) is associated with lower response to H. pylori therapy Not present in primary large B-cell gastric lymphoma Are typically indolent disease processes 6. A patient presents with an elevated WBC count, and flow cytometry is performed. Based on the dot plots shown on the website images for this case, what is the best diagnosis? Hematopathology - Part 5, Case #1 Hematopathology - Part 5, Case #1 Hematopathology - Part 5, Case #1 Hematopathology - Part 5, Case #1 Hematopathology - Part 5, Case #1T-cell ALL B-cell ALL Mantle cell lymphoma Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaPeripheralized Marginal Zone Lymphoma 7. Mantle Cell Lymphoma is associated with which of the following:t(11;18)t(14;18)t(2;5)t(11;14)t(8;14) 8. Which of the following chromosomal abnormalities is commonly found in multiple myeloma:+5 del 14 del 8 13q14 or monosomy 13 +3 9. A 12 year old boy presents with a WBC of 233K. The bone marrow aspirate with a myeloperoxidase stain are shown. Flow cytometry demonstrated CD19 positivity. What is the best diagnosis? Hematopathology - Part 5, Case #6 Hematopathology - Part 5, Case #6 Hematopathology - Part 5, Case #6. Myeloperoxidase (MPO).Pre B-ALL Pre T-ALL APLAML-M2 with t(8;21) AML-M4 10. Which of the following are associated with a worse prognosis in CLL/SLL:All of the answers are correct Del 13q14 CD38 expression on flow cytometry and trisomy 12Trisomy 12 Loading...