PathMD Quizes, Lung Lung – 03 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Approximately what percentage of cases of newly diagnosed lung cancer occur in heavy smokers (or those who recently quit)?>95%80%60%25%40% 2. Gain of function mutations (e.g. tyrosine kinase mutations) in lung cancer are most commonly associated with which of the following subtypes:Small Cell CarcinomaAdenocarcinomaCarcinoidSquamous Cell CarcinomaLarge Cell Carcinoma 3. As part of the manifestation of paraneoplastic syndromes, ADH is most commonly associated with what lung carcinoma subtype?Large Cell CarcinomaLarge Cell Neuroendocrine CarcinomaSquamous Cell CarcinomaAdenocarcinomaSmall Cell Carcinoma 4. Which of the following is least helpful in differentiating between a typical and atypical carcinoid?Tumor sizePresence of necrosisGrowth patternPresence of lymphatic invasionMitotic index 5. Adenocarcinoma in situ of the lung should not have evidence of invasion, and should be less than:3 cm2 cm0.5 cm1 cm1.5 cm 6. Which of the following activating mutations is NOT associated with a response to targeted therapy (e.g. tyrosine kinase inhibitors)?c-METROS-1ALKEGFRKRAS Loading...