PathMD Quizes, Lung Lung – 03 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Approximately what percentage of cases of newly diagnosed lung cancer occur in heavy smokers (or those who recently quit)?25%40%60%80%>95% 2. Adenocarcinoma in situ of the lung should not have evidence of invasion, and should be less than:1 cm3 cm0.5 cm1.5 cm2 cm 3. Which of the following activating mutations is NOT associated with a response to targeted therapy (e.g. tyrosine kinase inhibitors)?c-METROS-1EGFRALKKRAS 4. Which of the following is least helpful in differentiating between a typical and atypical carcinoid?Growth patternTumor sizePresence of lymphatic invasionPresence of necrosisMitotic index 5. Gain of function mutations (e.g. tyrosine kinase mutations) in lung cancer are most commonly associated with which of the following subtypes:Large Cell CarcinomaAdenocarcinomaCarcinoidSquamous Cell CarcinomaSmall Cell Carcinoma 6. As part of the manifestation of paraneoplastic syndromes, ADH is most commonly associated with what lung carcinoma subtype?Large Cell CarcinomaAdenocarcinomaSmall Cell CarcinomaSquamous Cell CarcinomaLarge Cell Neuroendocrine Carcinoma Loading...