Odontogenic Lesions – 01

Author:  Philip Ferguson, M.D.

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1. Which of the following tumors is characterized by sheets of hyperchromatic, pleomorphic cells with foci of mineralization. These islands and sheets of cells are dispersed throughout a nonspecific fibrous stroma. Foci of eosinophilic material c/w amyloid by congo red staining are also found with this tumor. The best diagnosis is:
2. All of the following are specific patterns of an ameloblastoma EXCEPT:
3. This lesion is characterized by thin layer of para-keratinized stratified squamous epithelium with a corrugated appearance and a prominent palisaded basal layer. The best diagnosis is:
4. This lesion arose in a 25 y/o male, and was associated with an embedded tooth. Based on the images for Case #1 in the images below, the best diagnosis is:

Odontogenic Part 1, Case #1
Odontogenic Part 1, Case #1


Odontogenic Part 1, Case #1
Odontogenic Part 1, Case #1


Odontogenic Part 1, Case #1
Odontogenic Part 1, Case #1
5. A 30 y/o male presents with a cystic odontogenic lesion. Based on the findings in the images associated with Case #5 below, the best diagnosis is:

Odontogenic Part 1, Case #5
Odontogenic Part 1, Case #5


Odontogenic Part 1, Case #5
Odontogenic Part 1, Case #5


Odontogenic Part 1, Case #5
Odontogenic Part 1, Case #5
6. Which of the following embryologic elements is responsible for the formation of dentin?
7. A 12 year old male presented to a dental office with an asymptomatic swelling of the right posterior mandible. He was referred to an oral surgeon, and representative images of the histology are presented in Case #6 below. Based on the findings, the best diagnosis is:

Odontogenic Part 1, Case #6
Odontogenic Part 1, Case #6


Odontogenic Part 1, Case #6
8. This cyst develops from epithelial rests of Malassez after tooth development, has a non-keratinized squamous epithelial lining, and is located at the root of a non-vital tooth. The best diagnosis is:
9. A 30 y/o male presents with an odontogenic lesion. Based on the findings in the images associated with Case #4 below, the best diagnosis is:

Odontogenic Part 1, Case #4
Odontogenic Part 1, Case #4


Odontogenic Part 1, Case #4
Odontogenic Part 1, Case #4
10. A cystic lesion is found in a 27 y/o female. Based on the images for Case #2 on the website for this question set, the best diagnosis is:

Odontogenic Part 1, Case #2
Odontogenic Part 1, Case #2


Odontogenic Part 1, Case #2
Odontogenic Part 1, Case #2
11. Tomes’ fibers, which are 200µm long unmyelinated nerve fibers, are found in which of the following tooth associated structures, and are responsible for sensation?
12. All of the following are needed to accurately classify an odontogenic cyst EXCEPT:
13. Cysts that occur at the junctions of developing structures in the head and neck are called:
14. A cystic lesion arises in a 32 y/o male. Based on the images below for Case #3, the best diagnosis is:

Odontogenic Part 1, Case #3
Odontogenic Part 1, Case #3