PathMD Quizes, Clinical, Hematopathology Peripheral Blood – 04 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. The image shown is from a 40 year old female who had a routine CBC, which showed thrombocytopenia (60K). Which of the following best explains her abnormalities? Peripheral Blood - Part 4, Question #6 Peripheral Blood - Part 4, Question #6 Peripheral Blood - Part 4, Question #6Bernard Soulier DiseaseMay Hegglin Anomaly Chediak-Higashi Erhlichia infection Acute infection 2. When considering hemoglobin electrophoresis on cellulose acetate at pH 8.4, which of the following is the correct order of Hb migration from the cathode towards the anode?C S F AC S A F A F S C S C A F S C F A 3. A 3 year old male is found to have “immature” cells in the peripheral blood that are myeloperoxidase negative. Flow cytometry is performed. Based on the findings, what is the best diagnosis? Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1Precursor B cell ALLNone of the answers are correctAnaplastic Large Cell Lymphoma Precursor T cell ALLAcute myelogenous leukemia with monocytic differentiation 4. The blood smear in this patient comes from a 21 year old male with a mother who has hereditary elliptocytosis. What is the most likely diagnosis? Peripheral Blood - Part 4, Question #5 Peripheral Blood - Part 4, Question #5Disseminated intravascular coagulation Microangiopathic hemolytic anemiaHereditary pyropoikilocytosisThermal injuryNone of the answers are correct 5. Abnormal lymphoid cells are identified in the blood of a 65 year old male. Flow cytometry is performed. Based on the findings, what is the best diagnosis? Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2Marginal zone lymphomaCLL/SLLPrecursor B Cell ALLMantle Cell Lymphoma Follicular Lymphoma – Peripheralized 6. A 45 year old woman presents to the ED with shortness of breath. A CBC was performed and the peripheral blood smear is shown. Based on the findings, what will the patient most likely be found to have? Peripheral Blood - Part 4, Question #4 Peripheral Blood - Part 4, Question #4Positive DAT with IgG and complement Positive monospot test Anti-i antibody M-spike on SPEPAnti-I antibody 7. A 60 year old Japanese male presents with abnormal clover-leaf appearing lymphoid cells in the peripheral blood. Flow cytometry is performed. Based on the findings, what is the best diagnosis? Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3Diffuse large B-cell lymphomaPrecursor T cell ALLAdult T cell leukemia/lymphoma Anaplastic large cell lymphomaAngioimmunoblastic T cell lymphoma 8. Tests for hemoglobin solubility are most useful in which of the following situations?Distinguishing HbC(Harlem) from HbS Distinguishing HbD from HbS Differentiating a thalassemia from a hemoglobinopathy None of the answers are correctDiagnosing sickle cell trait Loading...