PathMD Quizes, Clinical, Hematopathology Peripheral Blood – 04 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. The blood smear in this patient comes from a 21 year old male with a mother who has hereditary elliptocytosis. What is the most likely diagnosis? Peripheral Blood - Part 4, Question #5 Peripheral Blood - Part 4, Question #5Microangiopathic hemolytic anemiaThermal injuryNone of the answers are correctDisseminated intravascular coagulation Hereditary pyropoikilocytosis 2. Tests for hemoglobin solubility are most useful in which of the following situations?Distinguishing HbD from HbS Distinguishing HbC(Harlem) from HbS Diagnosing sickle cell trait None of the answers are correctDifferentiating a thalassemia from a hemoglobinopathy 3. Abnormal lymphoid cells are identified in the blood of a 65 year old male. Flow cytometry is performed. Based on the findings, what is the best diagnosis? Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2 Peripheral Blood - Part 4, Question #2Precursor B Cell ALLMarginal zone lymphomaMantle Cell Lymphoma Follicular Lymphoma – PeripheralizedCLL/SLL 4. A 3 year old male is found to have “immature” cells in the peripheral blood that are myeloperoxidase negative. Flow cytometry is performed. Based on the findings, what is the best diagnosis? Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1 Peripheral Blood - Part 4, Question #1Acute myelogenous leukemia with monocytic differentiation None of the answers are correctPrecursor B cell ALLAnaplastic Large Cell Lymphoma Precursor T cell ALL 5. The image shown is from a 40 year old female who had a routine CBC, which showed thrombocytopenia (60K). Which of the following best explains her abnormalities? Peripheral Blood - Part 4, Question #6 Peripheral Blood - Part 4, Question #6 Peripheral Blood - Part 4, Question #6Acute infection Bernard Soulier DiseaseChediak-Higashi May Hegglin Anomaly Erhlichia infection 6. When considering hemoglobin electrophoresis on cellulose acetate at pH 8.4, which of the following is the correct order of Hb migration from the cathode towards the anode?A F S C C S A F S C A F C S F AS C F A 7. A 60 year old Japanese male presents with abnormal clover-leaf appearing lymphoid cells in the peripheral blood. Flow cytometry is performed. Based on the findings, what is the best diagnosis? Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3 Peripheral Blood - Part 4, Question #3Adult T cell leukemia/lymphoma Angioimmunoblastic T cell lymphomaDiffuse large B-cell lymphomaPrecursor T cell ALLAnaplastic large cell lymphoma 8. A 45 year old woman presents to the ED with shortness of breath. A CBC was performed and the peripheral blood smear is shown. Based on the findings, what will the patient most likely be found to have? Peripheral Blood - Part 4, Question #4 Peripheral Blood - Part 4, Question #4Anti-I antibodyPositive DAT with IgG and complement Anti-i antibody M-spike on SPEPPositive monospot test Loading...