Organ Systems, Bone Marrow, Lymph Node, WHO Classification

Primary Effusion Lymphoma (PEL)

October 10, 2017 peferguson

Primary Effusion Lymphoma (PEL) is a rare form of DLBCL associated with HIV infection.

Immunophenotypic Expression Pattern

Marker	Comment
CD3	Negative
CD20	Variable (often negative)
CD138	Positive
CD30	Positive
EMA	Positive
EBV (EBER)	Positive (majority of cases)
HHV-8	Positive

References

Parker, A., et. al. “Best Practice in Lymphoma Diagnosis and Reporting.” British Committee for Standards in Haematology, Royal College of Pathologists. April, 2010.