PathMD Quizes, Renal Renal Neoplasms – 02 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Which of the following is most helpful in differentiating chromophobe RCC from an oncocytoma:Granular cytoplasm Perinuclear halosBinucleationPleomorphism 2. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorNone of the aboveRenal Cell Carcinoma, ChromophobeRenal Cell Carcinoma, Conventional OncocytomaRenal Cell Carcinoma, Papillary 3. According to the AJCC staging manual, all of the following affect the pathological staging of renal cell carcinoma EXCEPT:Extension into perinephric fat Extension into renal sinus fat SizeRenal vein involvement Fuhrman grade 4. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorNone of the aboveRenal Cell Carcinoma, PapillaryRenal Cell Carcinoma, Conventional Renal Cell Carcinoma, ChromophobeOncocytoma 5. The image below shows a renal tumor stained with Hale’s Colloidal Iron. The most likely diagnosis is: Renal Tumor Hale's Colloidal IronRCC, chromophobe type OncocytomaRCC, papillary type RCC, sarcomatoid type RCC, conventional type 6. A renal tumor has predominantly clear cells with the highest grade area containing cells with irregular nuclear border (size ~20m) and nucleoli visible from 10X. Many of the cells are noted to have eccentrically placed nuclei and eosinophilic cytoplasm. The best Fuhrman grade is:Fuhrman grade IIIFuhrman grade IFuhrman grade IIFuhrman grade IVFuhrman grade V 7. A 30 y/o African American male whose mother has sickle cell disease, is found to have a renal mass by CT examination. Which of the following are the most likely histologic features of this mass:Tubular Mucinous Spindle cell RCC Tubulopapillary architecture of infiltrating cells some with a hobnail like appearance. Tumor cell nuclei are high grade. Clear cells with abundant cytoplasm, irregular nuclei, and a fine network of thin walled vessels surrounding nests of cells. Papillary cores filled with foamy macrophages admixed with other areas of tubular and solid architecture. The cytoplasm is acidophilic, and no clear cell component is identified. Reticular / yolk sac-like pattern with focal areas having an adenoid-cystic pattern. 8. A 5 cm mass is removed from a 41 y/o female which is found to have areas of smooth muscle cells, blood vessels, and fat. Special stains for HMB-45 were positive. This lesion is associated with all of the following conditions EXCEPT:Birt-Hogg-Dube syndrome von Hippel-Lindau (VHL) syndrome Tuberous sclerosis von Recklinghausen disease 9. This tumor from the kidney illustrated in images below was negative for S-100 and desmin. In other areas of the tumor, RCC marker was focally positive. Which of the following is the best diagnosis? Renal Tumor Renal TumorRCC, Fuhrman grade IV LeiomyomaMetastatic malignant melanoma RhabdomyosarcomaNone of the above 10. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorRenal Cell Carcinoma, Conventional OncocytomaNone of the above Renal Cell Carcinoma, Papillary Renal Cell Carcinoma, Chromophobe 11. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal Tumor Renal TumorNone of the above Renal cell carcinoma, papillary typeRhabdomyosarcomaMetanephric adenoma Wilm’s tumor 12. Which of the following result in the highest stage for a renal cell carcinoma according to the 2002 AJCC staging manual:Metastasis to one single regional lymph nodeTumor invades beyond Gerota’s fasciaTumor grossly extends into the vena cava above the diaphragmTumor directly invades adrenal gland Tumor grossly invades the wall of the vena cava 13. An incidental renal lesion <1cm with papillary features and composed of predominantly clear cells is best classified as:Papillary adenoma Renal cell carcinoma, NOSRenal cell carcinoma, clear cell type Renal cell carcinoma, chromophil typePapillary carcinoma 14. An 18 y/o Caucasian male is found to have a renal tumor with clear cell RCC histology. It is important to perform cytogenetic analysis on this mass to look for involvement of which of the following chromosomes:3pXp11.2Chromosome 7Chromosome 11p13 None of the above Loading...
Renal Tumor
Renal Tumor
