PathMD Quizes, Clinical Statistics – 01 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Of the series of numbers { 1,3,3,3,4,5,5,7,8 }, calculate the mode, median, and mean, respectively.5,4,4.33 4,5,4.334,4,4.33 3,4,4.333,3,4.33 2. To validate a previously established reference range, what is the minimal number of healthy person samples needed?20018020As many as possible120 3. For a test without a Gaussian distribution, what is the minimal number of representative samples needed to establish a reference range?200As many as possible18020120 4. Which of the following correlation coefficients (r) represents the minimal number you would like to see when validating a new test?0.970.99None of the answers0.30.9 5. If 20 tests were performed on a “healthy” individual, what is the likelihood all of the results will be within the reference range?36%60%95%None of the answers46% 6. A series of data for a new clinical lab test has a Gaussian distribution. What percent of the data will be more than 3 standard deviations above the mean?None of the answers0.15%0.3%2.25%4.5% 7. A new instrument is installed for CBCs, and a correlation test is performed. The reference method is plotted on the X-axis and the new method on the Y-axis for multiple samples tested. Linear regression analysis is performed (y=mx + b). Which of the following represents the correlation coefficient, r?Line slope (m) Y-intercept (b) Calculation of how well the points fit the line None of the answers 8. For a test with a Gaussian distribution, what is the minimum number of representative samples needed to determine a reference range?20As many as possible200120180 9. Of the following answers, which is the best tool to detect bias between two different methods?T-test Bland-Altman plot Linear regression analysis Gaussian distributions F-test 10. The coefficient of variation best represents which of the following:AccuracyBiasNone of the answerPrecisionEfficiency Loading...