PathMD Quizes, Clinical Statistics – 01 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Which of the following correlation coefficients (r) represents the minimal number you would like to see when validating a new test?0.99None of the answers0.90.970.3 2. For a test without a Gaussian distribution, what is the minimal number of representative samples needed to establish a reference range?120As many as possible20020180 3. A series of data for a new clinical lab test has a Gaussian distribution. What percent of the data will be more than 3 standard deviations above the mean?None of the answers0.3%2.25%4.5%0.15% 4. To validate a previously established reference range, what is the minimal number of healthy person samples needed?As many as possible18012020020 5. The coefficient of variation best represents which of the following:AccuracyBiasPrecisionEfficiencyNone of the answer 6. A new instrument is installed for CBCs, and a correlation test is performed. The reference method is plotted on the X-axis and the new method on the Y-axis for multiple samples tested. Linear regression analysis is performed (y=mx + b). Which of the following represents the correlation coefficient, r?Y-intercept (b) None of the answersLine slope (m) Calculation of how well the points fit the line 7. If 20 tests were performed on a “healthy” individual, what is the likelihood all of the results will be within the reference range?46%None of the answers60%95%36% 8. For a test with a Gaussian distribution, what is the minimum number of representative samples needed to determine a reference range?As many as possible12020200180 9. Of the series of numbers { 1,3,3,3,4,5,5,7,8 }, calculate the mode, median, and mean, respectively.3,4,4.335,4,4.33 3,3,4.33 4,4,4.33 4,5,4.33 10. Of the following answers, which is the best tool to detect bias between two different methods?Linear regression analysis F-test Bland-Altman plot T-test Gaussian distributions Loading...