Molecular Testing Specimen Adequacy Summary
- JAK2, CALR, and MPL testing is often performed on peripheral blood specimens in an outpatient setting.
- JAK2 mutations are preferably analyzed in granulocytes.
- Peripheral blood and bone marrow specimens are equally adequate for the identification of JAK2 mutations.
- By extrapolation, CALR and MPL testing on peripheral blood specimens should be equally adequate.
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