PathMD Quizes, Clinical, Head & Neck Thyroid October 29, 2017 peferguson Author: Max Llaudes, M.D. & Joshua Bornhorst, Ph.D. Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Which is the best indicator of thyroxine abuse?Radioactive Iodine uptakeThyroglobulin level TSH levelAnti-thyroid peroxidase levelUltrasound of the thyroid 2. Which of the following statements regarding the biological effects of thyroid hormone is correct?None of the above statements is correctTheir biological effects are mediated by interactions between the hormone and cell membrane receptorsA cellular transmembrane tyrosine kinase receptor mediates the biological effects of thyroid hormoneThe thyroid hormone receptors are free intracellular proteins with high specificity and affinity for thyroid hormone binding sitesThe thyroid hormone water solubility allows to permeate through the cell membrane and bind intranuclear protein receptors 3. A 34 year old female with history of hypothyroidism controlled with l-thyroxine comes to the office for her 8-week prenatal check-up. Her vital signs and physical examination are non-contributory. What is the appropriate management of the hypothyroidism in this patient?Decrease the dose of L-thyroxineMeasure the T4 concentrationDiscontinue L-thyroxineIncrease the dose of L-thyroxineObservation and thyroid studies at 24 weeks 4. In the presence of a TSH secreting pituitary tumorFree T4 decreasesFree T3 increasesHypothyroidism results due to hypothalamic suppression effectThe radioactive iodine uptake decreasesThyroglobulin decreases 5. Which of the following is not a feature of Autoimmune Hashimoto thyroiditisAnti-thyroglobulin antibodiesIt may present as an enlarging thyroid glandAntibodies to the TSH receptorAnti-thyroid peroxidase antibodies 6. Which of the following conditions will present with a reduced radioactive iodine uptakePainless thyroiditisAmiodarone-induced thyrotoxicosisPost-partum thyroiditisAll of the above will result in a reduced uptake of radioactive iodineIodine-induced thyrotoxicosis 7. Which of the following conditions does not usually result in hypothyrodism?Subacute granulomatous thyroiditisUse of radioactive iodine for the treatment of Grave’s diseaseAll of the above conditions may result in hypothyroidismAutoimmune thyroiditisPostpartum thyroiditis 8. In Grave’s diseaseThe free thyroid is lowThe radioiodine uptake is lowThe thyroid gland shows nodular “hot” noduleThyroid Stimulating Immunoglobulins (TSI) are present in serum 9. Which of the following statements regarding the management of hypothyroid patients during pregnancy is correct?Continue the same dose of L-thyroxineThyroxine therapy needs to be discontinuedNone of the above statements is correctThyroxine requirements decrease due to transient hyperthyroidism of pregnancyThyroid hormone free levels increase during pregnancy 10. Which of the following statements regarding Euthyroid sick syndrome is correctThe levels of Free T4 are normal in moderate illnessCauses a marked elevation of TSH levelsResults in an increase in the peripheral conversion of T4 to T3Anti-thyroglobulin is present in high concentrations Loading...
