PathMD Quizes, Clinical, Head & Neck Thyroid October 29, 2017 peferguson Author: Max Llaudes, M.D. & Joshua Bornhorst, Ph.D. Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Which of the following is not a feature of Autoimmune Hashimoto thyroiditisIt may present as an enlarging thyroid glandAntibodies to the TSH receptorAnti-thyroid peroxidase antibodiesAnti-thyroglobulin antibodies 2. Which of the following conditions does not usually result in hypothyrodism?Postpartum thyroiditisAutoimmune thyroiditisSubacute granulomatous thyroiditisUse of radioactive iodine for the treatment of Grave’s diseaseAll of the above conditions may result in hypothyroidism 3. Which of the following statements regarding Euthyroid sick syndrome is correctAnti-thyroglobulin is present in high concentrationsCauses a marked elevation of TSH levelsResults in an increase in the peripheral conversion of T4 to T3The levels of Free T4 are normal in moderate illness 4. A 34 year old female with history of hypothyroidism controlled with l-thyroxine comes to the office for her 8-week prenatal check-up. Her vital signs and physical examination are non-contributory. What is the appropriate management of the hypothyroidism in this patient?Discontinue L-thyroxineIncrease the dose of L-thyroxineDecrease the dose of L-thyroxineObservation and thyroid studies at 24 weeksMeasure the T4 concentration 5. Which is the best indicator of thyroxine abuse?Radioactive Iodine uptakeUltrasound of the thyroid Thyroglobulin level TSH levelAnti-thyroid peroxidase level 6. Which of the following statements regarding the biological effects of thyroid hormone is correct?None of the above statements is correctTheir biological effects are mediated by interactions between the hormone and cell membrane receptorsThe thyroid hormone water solubility allows to permeate through the cell membrane and bind intranuclear protein receptorsA cellular transmembrane tyrosine kinase receptor mediates the biological effects of thyroid hormoneThe thyroid hormone receptors are free intracellular proteins with high specificity and affinity for thyroid hormone binding sites 7. Which of the following statements regarding the management of hypothyroid patients during pregnancy is correct?None of the above statements is correctThyroid hormone free levels increase during pregnancyContinue the same dose of L-thyroxineThyroxine therapy needs to be discontinuedThyroxine requirements decrease due to transient hyperthyroidism of pregnancy 8. In the presence of a TSH secreting pituitary tumorHypothyroidism results due to hypothalamic suppression effectFree T4 decreasesThe radioactive iodine uptake decreasesFree T3 increasesThyroglobulin decreases 9. Which of the following conditions will present with a reduced radioactive iodine uptakeAll of the above will result in a reduced uptake of radioactive iodineIodine-induced thyrotoxicosisAmiodarone-induced thyrotoxicosisPost-partum thyroiditisPainless thyroiditis 10. In Grave’s diseaseThe radioiodine uptake is lowThe thyroid gland shows nodular “hot” noduleThyroid Stimulating Immunoglobulins (TSI) are present in serumThe free thyroid is low Loading...
