PathMD Quizes, Clinical, Head & Neck Thyroid October 29, 2017 peferguson Author: Max Llaudes, M.D. & Joshua Bornhorst, Ph.D. Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. In the presence of a TSH secreting pituitary tumorThyroglobulin decreasesFree T4 decreasesThe radioactive iodine uptake decreasesHypothyroidism results due to hypothalamic suppression effectFree T3 increases 2. Which is the best indicator of thyroxine abuse?Thyroglobulin level TSH levelUltrasound of the thyroid Anti-thyroid peroxidase levelRadioactive Iodine uptake 3. Which of the following is not a feature of Autoimmune Hashimoto thyroiditisAntibodies to the TSH receptorIt may present as an enlarging thyroid glandAnti-thyroid peroxidase antibodiesAnti-thyroglobulin antibodies 4. Which of the following statements regarding the biological effects of thyroid hormone is correct?The thyroid hormone receptors are free intracellular proteins with high specificity and affinity for thyroid hormone binding sitesA cellular transmembrane tyrosine kinase receptor mediates the biological effects of thyroid hormoneTheir biological effects are mediated by interactions between the hormone and cell membrane receptorsNone of the above statements is correctThe thyroid hormone water solubility allows to permeate through the cell membrane and bind intranuclear protein receptors 5. Which of the following conditions does not usually result in hypothyrodism?Subacute granulomatous thyroiditisPostpartum thyroiditisAll of the above conditions may result in hypothyroidismAutoimmune thyroiditisUse of radioactive iodine for the treatment of Grave’s disease 6. Which of the following statements regarding the management of hypothyroid patients during pregnancy is correct?Continue the same dose of L-thyroxineThyroxine therapy needs to be discontinuedThyroid hormone free levels increase during pregnancyNone of the above statements is correctThyroxine requirements decrease due to transient hyperthyroidism of pregnancy 7. Which of the following statements regarding Euthyroid sick syndrome is correctCauses a marked elevation of TSH levelsAnti-thyroglobulin is present in high concentrationsThe levels of Free T4 are normal in moderate illnessResults in an increase in the peripheral conversion of T4 to T3 8. Which of the following conditions will present with a reduced radioactive iodine uptakeIodine-induced thyrotoxicosisAll of the above will result in a reduced uptake of radioactive iodineAmiodarone-induced thyrotoxicosisPainless thyroiditisPost-partum thyroiditis 9. A 34 year old female with history of hypothyroidism controlled with l-thyroxine comes to the office for her 8-week prenatal check-up. Her vital signs and physical examination are non-contributory. What is the appropriate management of the hypothyroidism in this patient?Measure the T4 concentrationIncrease the dose of L-thyroxineDiscontinue L-thyroxineObservation and thyroid studies at 24 weeksDecrease the dose of L-thyroxine 10. In Grave’s diseaseThe radioiodine uptake is lowThyroid Stimulating Immunoglobulins (TSI) are present in serumThe thyroid gland shows nodular “hot” noduleThe free thyroid is low Loading...